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Allele : Nppc<tm1.1Fgr> natriuretic peptide type C; targeted mutation 1.1, Fritz G Rathjen

Primary Identifier  MGI:4365461 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Nppc
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 1 was replaced with a lacZ with a nuclear localization signal and a floxed cre-neo cassette, which excises itself. Exon 2 was also modified to introduce STOP codons in all three frames. The absence of protein expression as confirmed by immunohistochemistry on E12.5 spinal cord sections.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • CNPlacZ<->,
  • Nppc<lacZ>,
  • Nppc<lacZ>,
  • CNPlacZ<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories