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Allele : F2r<tm1.1Cgh> coagulation factor II thrombin receptor; targeted mutation 1.1, Shaun R Coughlin

Primary Identifier  MGI:4365911 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  F2r
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The starting ATG codon as well as codons 2-4 of exon 1 were replaced with a lacZ-floxed PGKneo cassette. The neo cassette was in the same transcriptional orientation as the gene itself. In vivo cre excision was accomplished by crossing to Tg(ACTB-cre)2Mrt transgenic mice. After cre excision of neo, beta galactosidase staining was reduced in intensity but the overall pattern of staining was maintained.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Par1-LacZ,
  • Par1-LacZ
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

7 Publication categories