Primary Identifier | MGI:4366749 | Allele Type | Targeted |
Gene | Bcl2l11 | Transmission | Germline |
Strain of Origin | B6.Cg-Thy1<a> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The BH3 domain (in exon 5) was replaced by the mouse Bad BH3 domain by site-directed mutagenesis using PCR. A loxP-PGKneo-loxP cassette was inserted 840 bp downstream of exon 5. The neo cassette was removed by crossing the mice to cre deleter transgenic mice. |