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Allele : Bcl2l11<tm2.1Boui> BCL2 like 11; targeted mutation 2.1, Philippe Bouillet

Primary Identifier  MGI:4366751 Allele Type  Targeted
Gene  Bcl2l11 Transmission  Germline
Strain of Origin  B6.Cg-Thy1<a> Is Recombinase  false
Is Wild Type  false
molecularNote  The BH3 domain (in exon 5) was replaced by the mouse Pmaip1 (Noxa) BH3 domain by site-directed mutagenesis using PCR. A loxP-PGKneo-loxP cassette was inserted 840 bp downstream of exon 5. The neo cassette was removed by crossing the mice to cre deleter transgenic mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Bim<Noxa>,
  • Bim<N>,
  • Bim<Noxa>,
  • Bim<N>,
  • Bim<Noxa>,
  • Bim<N>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

0 Driven By

6 Publication categories