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Allele : Bcl2l11<tm3.1Boui> BCL2 like 11; targeted mutation 3.1, Philippe Bouillet

Primary Identifier  MGI:4366756 Allele Type  Targeted
Gene  Bcl2l11 Transmission  Germline
Strain of Origin  B6.Cg-Thy1<a> Is Recombinase  false
Is Wild Type  false
molecularNote  The BH3 domain (in exon 5) was replaced by the mouse Bbc3 (Puma) BH3 domain by site-directed mutagenesis using PCR. A loxP-PGKneo-loxP cassette was inserted 840 bp downstream of exon 5. The neo cassette was removed by crossing the mice to cre deleter transgenic mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Bim<P>,
  • Bim<Puma>,
  • Bim<P>,
  • Bim<Puma>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

6 Publication categories