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Allele : Pla2g6<m1J> phospholipase A2, group VI; mutation 1, Jackson

Primary Identifier	MGI:4412026	Allele Type	Spontaneous
Gene	Pla2g6	Inheritance Mode	Recessive
Strain of Origin	C3H/HeJ	Is Recombinase	false
Is Wild Type	false

molecularNote

A viral insertion occurred spontaneously in intron 1 upstream of the start codon, resulting in a dramatic reduction of transcript levels.

mutations:
Viral insertion

earliestPublication:
Strokin M, et al. (2012) Severe disturbance in the Ca2+ signaling in astrocytes from mouse models of human infantile neuroaxonal dystrophy with mutated Pla2g6. Hum Mol Genet 21(12):2807-14

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

4 Carried By

0 Driven By

5 Publication categories

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