| Primary Identifier | MGI:4414655 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Il1rapl1 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of exon 5 and a floxed hygro cassete was inserted downstream of exon 5. Cre mediated recombination removed exon 5 and the hygro cassette. Removal of exon 5 results in a frame shift and premature termination at amino acid 186. The absence of protein expression was confirmed by western blot analysis on brain extracts. |
