| Primary Identifier | MGI:4418309 | Allele Type | Targeted |
| Attribute String | Hypomorph | Gene | Adam8 |
| Transmission | Germline | Strain of Origin | DBA/1LacJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A glutamic acid at residue 330 was mutated to a glutamine by a point mutation in exon 11. The targeting vector contained a loxP-flanked neomycin cassette, that was removed by cre-mediated recombination. An activity assay confirmed the absence of ADAM8 peptidase activity in cells from homozygous mice. |
