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Allele : Ctnnb1<tm4.1Wbm> catenin beta 1; targeted mutation 4.1, Walter Birchmeier

Primary Identifier  MGI:4429437 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ctnnb1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted into the second intron and a loxP-flanked neomycin selection cassette was inserted into the sixth intron. The neomycin cassette was removed by transient expression of Cre recombinase in ES cells prior to the production of chimeric mice, leaving two loxP sites that flank exons 3-6 in the final allele. Exons 3-6 were excised by Cre mediated recombination.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Ctnnb1<->,
  • Ctnnb1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories