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Allele : Gt(ROSA)26Sor<tm7(Pik3ca*,EGFP)Rsky> gene trap ROSA 26, Philippe Soriano; targeted mutation 7, Klaus Rajewsky
Primary Identifier  MGI:4430527 Allele Type  Targeted
Attribute String  Conditional ready, Constitutively active, Inserted expressed sequence, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  The P110*-transgene is a targeting vector designed with (from 5' to 3') a splice acceptor site, a loxP-flanked Neo-STOP cassette, a cDNA sequence encoding P110* (a constituitively active form of mouse P110alpha [Pik3ca; the catalytic subunit of phosphatidylinositol 3-kinase]), an FRT-flanked internal ribosomal entry site-enhanced green fluorescent protein cassette (IRES-EGFP), and bovine polyadenylation signal. This transgene construct was inserted between exons 1 and 2 of the Gt(ROSA)26Sor locus.
  • mutations:
  • Insertion
  • synonyms:
  • R26Stop flox P110*,
  • ROSA26-STOP-PI3KDA,
  • R26Stop-flox-P110*,
  • ROSA26-STOP-PI3KDA,
  • P110*-transgene,
  • R26Stop flox P110*,
  • R26Stop-flox-P110*,
  • P110*-transgene,
  • R26Stop<FL>P110*,
  • R26Stop<FL>P110*
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

38 Publication categories





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