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Allele : Gt(ROSA)26Sor<tm9(Rac1*,EGFP)Rsky> gene trap ROSA 26, Philippe Soriano; targeted mutation 9, Klaus Rajewsky
Primary Identifier  MGI:4430551 Allele Type  Targeted
Attribute String  Conditional ready, Constitutively active, Inserted expressed sequence, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector designed with (from 5' to 3') a splice acceptor site, a loxP-flanked Neo-STOP cassette, a cDNA sequence encoding RACDA (RacG12V; a mutant form of Rac1 rendered constitutively active by a glycine->valine substitution at amino acid 12]), an frt-flanked internal ribosomal entry site-enhanced green fluorescent protein cassette (IRES-EGFP), and bovine polyadenylation signal. This transgene construct was inserted between exons 1 and 2 of the Gt(ROSA)26Sor locus.
  • mutations:
  • Insertion
  • synonyms:
  • R26Stop-flox-RACDA,
  • LSL-Rac1<G12V>,
  • RacV12,
  • R26Stop<FL>RACDA,
  • Rac<G12V>,
  • R26Stop flox RACDA,
  • RacV12,
  • R26Stop-flox-RACDA,
  • R26Stop<FL>RACDA,
  • R26Stop flox RACDA,
  • Rac<G12V>,
  • LSL-Rac1<G12V>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

11 Publication categories





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