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Allele : Tnfrsf1a<tm2.1Rsie> tumor necrosis factor receptor superfamily, member 1a; targeted mutation 2.1, Richard M Siegel

Primary Identifier  MGI:4461135 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Tnfrsf1a
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was replaced with a floxed neo cassette and modified exon 2 in which nucleotide substitutions result in the amino acid substitution of tyrosine for cysteine at position 33 (C33Y), mimicking a mutation associated with TNFR-associated periodic syndrome (TRAPS). Cre mediated recombination removes the neo cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • TNFR1<C33Y>,
  • TNFR1<C33Y>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele