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Allele : Ago2<tm3.1Ghan> argonaute RISC catalytic subunit 2; targeted mutation 3.1, Greggory J Hannon
Primary Identifier  MGI:4462371 Allele Type  Targeted
Gene  Ago2 Transmission  Germline
Strain of Origin  (129S6/SvEvTac x C57BL/6NCrl)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Mice exhibit an A to C mutation that results in the amino acid substitution of alanine for aspartic acid at position 598 (D598A) within the catalytic DDH motif. A floxed neo cassette was removed by cre mediated recombination.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Ago2<ADH>,
  • Ago2<ADH>,
  • Ago2<D598A>,
  • Ago2<D598A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories





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