Primary Identifier | MGI:4837928 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Klf13 |
Transmission | Germline | Strain of Origin | 129S/SvEv-Gpi1<c> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The first intron, encoding the transactivation domain and the first of the protein's three zinc fingers, has been replaced with a neomycin resistance cassette. Reverse transcription followed by PCR (RT-PCR) of mRNA from hearts of homozygous mutant mice detects no transcripts from the targeted gene; heterozygous mice express approximately half the wild-type level of mRNA. |