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Allele : Fto<tm1.1Pzg> FTO alpha-ketoglutarate dependent dioxygenase; targeted mutation 1.1, Pumin Zhang

Primary Identifier	MGI:4868738	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Fto
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was inserted upstream of exon 3, and an FRT-flanked neo cassette with a 5' loxP site was inserted dowstream of exon 3. Flp-mediated recombination removed the neo cassette leaving exon 3 floxed.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Fto<flox>,
Fto<flox>

earliestPublication:
Gao X, et al. (2010) The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice. PLoS One 5(11):e14005

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

15 Publication categories

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