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Allele : Fto<tm1.2Pzg> FTO alpha-ketoglutarate dependent dioxygenase; targeted mutation 1.2, Pumin Zhang

Primary Identifier	MGI:4868744	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Fto
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

Cre mediated recombination removed exon 3 from Fto^tm1.1Pzg. The absence of protein expression was confirmed by western blot analysis on brain, white adipose, and brown adipose extracts.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Fto<#delta>,
Fto<#delta>

earliestPublication:
Gao X, et al. (2010) The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice. PLoS One 5(11):e14005

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

8 Publication categories

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