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Allele : Csf2/Il3<tm1.1(CSF2,IL3)Flv> interleukin 3; targeted mutation 1.1, Richard A Flavell

Primary Identifier  MGI:4887881 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Il3
Transmission  Germline Strain of Origin  BALB/cAnNTac x 129S4/SvJae
Is Recombinase  false Is Wild Type  false
description  Originally generated in ES cells containing Il2rgtm1.1Flv and Rag2tm1.1Flv.
molecularNote  The coding region of Il3 through Csf2 was replaced with the corresponding human sequence. The human Il3 remains under the control of the mouse promoter while expression of Csf2 is controlled by the human promoter. Cre-mediated recombination removed the selection cassettes.
  • mutations:
  • Insertion,
  • Intergenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

19 Publication categories