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Allele : Grem1<tm1.1Ecan> gremlin 1, DAN family BMP antagonist; targeted mutation 1.1, Ernesto Canalis

Primary Identifier  MGI:4941469 Allele Type  Targeted
Attribute String  Conditional ready Gene  Grem1
Transmission  Germline Strain of Origin  (129X1/SvJ x C57BL/6)F1
Is Recombinase  false Is Wild Type  false
molecularNote  This allele was derived from Grem1tm1Ecan by deletion of a frt -flanked selection cassette that, followed by a loxP site, replaced the non-conserved final 66 bp of the 3'-UTR. The present allele contains a loxP site 335 bp upstream of the coding region-encompassing second exon and, within exon 2, the remaining frt site and second loxP site 550 bp downstream of the termination codon.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories