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Allele : Mcpt8<tm1(cre)Lky> mast cell protease 8; targeted mutation 1, Richard M Locksley

Primary Identifier  MGI:5007937 Allele Type  Targeted
Attribute String  Recombinase Gene  Mcpt8
Transmission  Germline Strain of Origin  129S4/SvJae-Tg(Prm-cre)70Og
Is Recombinase  true Is Wild Type  false
molecularNote  A 4.8 kb reporter cassette containing YFP, IRES site, humanized cre recombinase, bGH polyA, and a loxP-flanked neo selection marker was inserted at the Mcpt8 start site via homologous recombination in ES cells contain PrmCre (PC3 cells with Tg(Prm-cre)70Og). Upon crossing male chimeras to wild-type females, the loxP-flanked neo was deleted from the male germline by cre recombination, producing the final knock-in allele.
  • mutations:
  • Insertion
  • synonyms:
  • Mcpt8<tm1(cre)Lksy>,
  • Basoph8,
  • Mcpt8<YFP-Cre>,
  • Basoph8,
  • Mcpt8<tm1(cre)Lksy>,
  • Mcpt8<YFP-Cre>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

1 Driven By

19 Publication categories