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Allele : Ptpn22<tm1.1Kas> protein tyrosine phosphatase, non-receptor type 22 (lymphoid); targeted mutation 1.1, Katherine A Siminovitch
Primary Identifier  MGI:5294241 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Ptpn22
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 14 was replaced with one in which a C to T transition (c.1967C>T) results in the amino acid substitution of tryptophan for arginine at position 619 (R619W). Cre-mediated recombination removed the floxed neo cassette upstream of the modified exon.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Pep619W,
  • Pep619W
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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