| Primary Identifier | MGI:5294790 | Allele Type | Targeted |
| Gene | Cdh5 | Transmission | Germline |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| description | This allele was generated from Cdh5tm1Dvst. |
| molecularNote | RMCE replaced exon 2 and the neo cassette in Cdh5tm1Dvst with a fusion of mouse Cdh5 lacking 75 C-terminal amino acids of the cytoplasmic tail and the C-terminal two-thirds of mouse alpha-catenin (amino acids 301-900), transcription stop sequence, and FRT-flanked hygro flanked by a loxP and a lox2272 site. A C to T mutation was inserted 2130 bp from the start codon to create a new ClaI site. |
