| Help | About | Contact Us

Allele : Fbxl5<tm1Kei> F-box and leucine-rich repeat protein 5; targeted mutation 1, Keiichi I Nakayama

Primary Identifier	MGI:5295288	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Fbxl5
Transmission	Germline	Strain of Origin	Not Specified
Is Recombinase	false	Is Wild Type	false

molecularNote

Exons 4 and 5 were replaced with an IRES-lacZ cassette and floxed neo cassette via homologous recombination. In situ hybridization analysis confirmed the absence of expression in homozygous mice.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Fbxl5<->,
Fbxl5<->

earliestPublication:
Moroishi T, et al. (2011) The FBXL5-IRP2 Axis Is Integral to Control of Iron Metabolism In Vivo. Cell Metab 14(3):339-51

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

4 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=76401065

MouseMine