| Primary Identifier | MGI:5298406 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Clec9a |
| Transmission | Germline | Strain of Origin | (129S6/SvEvTac x C57BL/6J)F1 |
| Is Recombinase | false | Is Wild Type | false |
| description | The expression of NK1.1 (Klrb1c) is linked to Clec9a deficiency in homozygous mice, indicating that the homologous recombination step targeted the chromosome of C57BL/6J origin. |
| molecularNote | A targeting vector was designed to replace the C-type lectin domain family 9, member a (Clec9a) coding region with a farnesylated form of enhanced green fluorescent protein (EGFP), a polyadenylation signal, and a loxP-flanked neomycin (neo) resistance cassette. Cre-mediated recombination removed the neo cassette. |
