Primary Identifier | MGI:5299185 | Allele Type | Targeted |
Gene | Tln1 | Transmission | Germline |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 10 was replaced with one in which a point mutation results in the amino acid substitution of leucine with arginine at position 325 (p.L325R) in the encoded protein. A loxP site flanked neomycin resistance gene cassette that was inserted into intron 10 was removed by subsequent cre-mediated recombination. |