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Allele : Tg(Acta2-cre/ERT2)#Pcn transgene insertion, Pierre Chambon

Primary Identifier	MGI:5305721	Allele Type	Transgenic
Attribute String	Inducible, Recombinase	Gene	Tg(Acta2-cre/ERT2)#Pcn
Strain of Origin	FVB/N	Induced With	tamoxifen
Is Recombinase	true	Is Wild Type	false

molecularNote

A construct containing cre fused to ERT2 followed by an frt flanked PGK-neo cassette was inserted at the initiation codon of Acta2 in a 175 kb mouse BAC. Tamoxifen-induced cre activity was seen in smooth muscle cells.

mutations:
Insertion

synonyms:
alphaSMA-Cre-ER<T2>,
alphaSMA-Cre-ER<T2>,
Sma<CreER>,
Sma<CreER>

earliestPublication:
Wendling O, et al. (2009) Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouse. Genesis 47(1):14-8

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

1 Driven By

75 Publication categories

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