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Allele : Grin2b<tm1.1Jwhe> glutamate receptor, ionotropic, NMDA2B (epsilon 2); targeted mutation 1.1, Johannes W Hell
Primary Identifier  MGI:5314923 Allele Type  Targeted
Gene  Grin2b Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 13 was replaced with one in which nucleotide substitutions (CTGCGCCGG to GCGCGCCAA) results in the amino acid substitution of alanine for leucine at positions 1298 (L1298A) and glutamine for arginine at position 1300 (Q1300R). Cre-mediated recombination removed the floxed neo cassette inserted downstream of the modified exon 13.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • GluN2B L1298A/R1300Q,
  • GluN2B L1298A/R1300Q
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

10 Publication categories





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