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Allele : Aven<tm1.1Zrng> apoptosis, caspase activation inhibitor; targeted mutation 1.1, Martin Zoernig

Primary Identifier  MGI:5317759 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Aven
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  The sequence within the first exon that encodes the first 200 amino acids of the protein has been replaced with a green fluorescent protein (GFP) cDNA that includes an ATG translation termination codon and a polyadenylation signal. GFP is therefore expressed under control of the endogenous promoter, and the endogenous protein is not expressed. A tk-neo cassette that was flanked by loxP sites in the original construct was deleted in vivo.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Aven<tm(GFP)>,
  • Aven<tm(GFP)>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories