Primary Identifier | MGI:5432227 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Grm1 |
Inheritance Mode | Semidominant | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The transgene contained a 2 kb segment of human cosmid p18A4 (known as Clone B; abbreviated here as p18A4.B). Line 1352 contains 3 copies of the transgene that insert into intron 3 and result in a 70 kb deletion within intron 3. Western blot analysis confirmed ectopic expression in melanoma tumors. |