Primary Identifier | MGI:5432496 | Allele Type | Targeted |
Gene | Spo11 | Transmission | Germline |
Strain of Origin | 129 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 5 was replaced by a modified exon 5 in which nucleotide substitution of a single A to T results in the amino acid substitution of phenylalanine for tyrosine at position 138 (Y138F). Two lox sites also remain inserted (one in intron 4, one in intron 9) after integration of the modified exon 5. |