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Allele : Spo11<tm1Bdm> SPO11 initiator of meiotic double stranded breaks; targeted mutation 1, Bernard de Massy

Primary Identifier  MGI:5432496 Allele Type  Targeted
Gene  Spo11 Transmission  Germline
Strain of Origin  129 Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 5 was replaced by a modified exon 5 in which nucleotide substitution of a single A to T results in the amino acid substitution of phenylalanine for tyrosine at position 138 (Y138F). Two lox sites also remain inserted (one in intron 4, one in intron 9) after integration of the modified exon 5.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • Spo11<YF>,
  • Spo11Y138F,
  • Spo11Y138F,
  • Spo11<YF>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele