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Allele : Ddit3<tm2.1Dron> DNA-damage inducible transcript 3; targeted mutation 2.1, David Ron

Primary Identifier	MGI:5441015	Allele Type	Targeted
Attribute String	Null/knockout, Reporter	Gene	Ddit3
Transmission	Germline	Strain of Origin	129S6/SvEvTac
Is Recombinase	false	Is Wild Type	false

molecularNote

A NLS-lacZ cassette and a floxed PGK-Neo cassette replaced the coding region in parts of exons 3 and 4. Cre-mediated recombination removed the neo cassette.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Chop<->,
CHOP::LacZ,
Chop<->,
CHOP::LacZ

earliestPublication:
Moisoi N, et al. (2009) Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response. Cell Death Differ 16(3):449-64

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

88 Publication categories

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