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Allele : Ccnd3<tm1.1(Ccnd2)Iaai> cyclin D3; targeted mutation 1.1, Iannis Aifantis

Primary Identifier	MGI:5468556	Allele Type	Targeted
Gene	Ccnd3	Transmission	Germline
Strain of Origin	129S6/SvEvTac	Is Recombinase	false
Is Wild Type	false

molecularNote

The coding sequence including introns was replaced with the murine cDNA. Cre-mediated recombination removed the floxed neo cassette downstream of the mouse cDNA. The 5' and 3' untranslated regions remain intact.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Ccnd3<D2>,
Ccnd3<Ccnd2>,
Ccnd3<D2>,
Ccnd3<Ccnd2>

earliestPublication:
Sawai CM, et al. (2012) Therapeutic targeting of the cyclin D3:CDK4/6 complex in T cell leukemia. Cancer Cell 22(4):452-65

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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