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Allele : Tg(Myh6-Gsk3b*)19Jusa transgene insertion 19, Junichi Sadoshima

Primary Identifier  MGI:5471797 Allele Type  Transgenic
Attribute String  Dominant negative, Inserted expressed sequence Gene  Tg(Myh6-Gsk3b*)19Jusa
Strain of Origin  FVB Is Recombinase  false
Is Wild Type  false
molecularNote  The promoter drives cardiac-specific expression of a modified cDNA in which nucleotide susbtitutions result in the amino acid substitution of methionine for lysine at position 85 (K85M) and isoleucine for lysine at position 86 (K86I). These mutations are predicted to produce a dominant negative product. Line 19 was generated.
  • mutations:
  • Insertion
  • synonyms:
  • Tg-GSK-3beta-KI,
  • Tg-GSK-3beta-KI,
  • DnGSK-3beta,
  • DnGSK-3beta
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories