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Allele : Spo11<tm2.1Rdco> SPO11 initiator of meiotic double stranded breaks; targeted mutation 2.1, R Daniel Camerini-Otero
Primary Identifier  MGI:5490537 Allele Type  Targeted
Gene  Spo11 Transmission  Germline
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 5 was replaced with a modified exon 5 in which nucleotide substitutions result in the amino acid substitutions of phenylalanine for tyrosine at positions 137 and 138 (Y137F, Y138F). Cre-mediated recombination removed the floxed neomycin resistance cassette that was inserted downstream of exon 8.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Spo11<YY137,138FF>,
  • Spo11<FF>,
  • Spo11<FF>,
  • Spo11<YY137,138FF>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories





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