Primary Identifier | MGI:5489890 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Egr3 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> |
Is Recombinase | true | Is Wild Type | false |
molecularNote | By homologous recombination, a targeting construct replaced the endogenous exon 1, intron, and exon 2 of Egr3 with a cassette encoding nuclear-localized cre recombinase with and a PGK-neo selection marker flanked with forward-oriented Frt sites. The neo was excised from the germline by mating mice to CAG-FLPe mice. |