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Allele : Fcmr<tm1Mak> Fc fragment of IgM receptor; targeted mutation 1, Tak Mak

Primary Identifier	MGI:5496253	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Fcmr
Transmission	Germline	Strain of Origin	129S2/SvPas
Is Recombinase	false	Is Wild Type	false

molecularNote

A neomycin selection cassette replaced almost the entire coding region, extending from an intron in the 5' leader sequence pasted the last methionine codon. PCR and RT-PCR of various tissue extracts confirmed gene deletion.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
Toso<->,
Toso<->

earliestPublication:
Lang KS, et al. (2013) Involvement of Toso in activation of monocytes, macrophages, and granulocytes. Proc Natl Acad Sci U S A 110(7):2593-8

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

10 Publication categories

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