| Primary Identifier | MGI:5499209 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Sirt2 |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of exon 5. An FRT-flanked neo cassette with a 5' loxP site was inserted downstream of exon 7. Flp-mediated recombination removed the neo cassette and left exons 5 through 7 floxed. Cre-mediated recombination removed exons 5 through 7. Western blot analysis confirmed the absence of protein expression in the spinal cord, brain and sciatic nerve. |
