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Allele : Ezr<tm1Sats> ezrin; targeted mutation 1, Sachiko Tsukita

Primary Identifier	MGI:5508539	Allele Type	Targeted
Attribute String	Null/knockout, Reporter	Gene	Ezr
Transmission	Germline	Strain of Origin	129S4/SvJae
Is Recombinase	false	Is Wild Type	false

molecularNote

A targeting construct inserted into intron 2 a splice acceptor, IRES, lacZ, neomycin resistance cassette and polyadenylation sequence. Immunoblotting confirmed protein expression in small amounts in the stomach.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
Ez<->,
Vil2<kd>,
Ez<->,
Vil2<kd>

earliestPublication:
Tamura A, et al. (2005) Achlorhydria by ezrin knockdown: defects in the formation/expansion of apical canaliculi in gastric parietal cells. J Cell Biol 169(1):21-8

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

9 Publication categories

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