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Allele : Kidins220<tm1.2Fces> kinase D-interacting substrate 220; targeted mutation 1.2, Fabrizia Cesca

Primary Identifier  MGI:5527339 Allele Type  Targeted
Attribute String  Null/knockout Gene  Kidins220
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed corresponding cDNA with a polyadenylation sequence was inserted upstream of exon 16. An IRES, lacZ and polyadenylation sequence followed by an FRT-flanked neomycin resistance cassette replaced exon 17. Flp-mediated recombination removed the neomycin resistance cassette. Cre-mediated recombination removed the cDNA. Western blot analysis confirmed the absence of protein expression in E18 embryos.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

11 Publication categories