| Help | About | Contact Us

Allele : Itgb1<tm14.1Ref> integrin beta 1 (fibronectin receptor beta); targeted mutation 14.1, Reinhard Fassler

Primary Identifier	MGI:5529145	Allele Type	Targeted
Gene	Itgb1	Transmission	Germline
Strain of Origin	Not Specified	Is Recombinase	false
Is Wild Type	false

molecularNote

Nucleotide substitution(s) result(s) in the amino acid substitution of an alanine for tyrosine at position 795 (Y795A). Cre-mediated recombination removed the floxed neomycin resistance cassette.

mutations:
Insertion,
Nucleotide substitutions

cellLines:
Not Specified

synonyms:
beta1 Y795A,
beta1 Y795A

earliestPublication:
Bottcher RT, et al. (2012) Sorting nexin 17 prevents lysosomal degradation of beta1 integrins by binding to the beta1-integrin tail. Nat Cell Biol 14(6):584-92

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

6 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=76488477

MouseMine