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Allele : Irak2<tm1.1Pcoh> interleukin-1 receptor-associated kinase 2; targeted mutation 1.1, Philip Cohen

Primary Identifier  MGI:5548123 Allele Type  Targeted
Attribute String  Hypomorph Gene  Irak2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A GAA to GCA nucleotide substitution results in the amino acid substitution of alanine for glutamic acid at position 525 (E525A). Flp-mediated recombination removed the selection cassettes. The modified exon remains floxed.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • IRAK2[E525A],
  • IRAK2[E525A]
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories