Primary Identifier | MGI:5571475 | Allele Type | Targeted |
Attribute String | Inducible, Null/knockout, Recombinase | Gene | Kit |
Transmission | Germline | Strain of Origin | 129/Sv |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
molecularNote | A cDNA encoding MerCreMer (cre recombinase fused to two modified estrogen receptor ligand binding domains at both ends), and an frt-flanked neomycin selection cassette were cloned in-frame with the Kit ATG start site. Homologous recombination was performed in ES cells, and chimeras were bred to flp-expressing knock-in mice to delete the selection marker. |