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Allele : Themis<m1Btlr> thymocyte selection associated; mutation 1, Bruce Beutler

Primary Identifier  MGI:5575394 Allele Type  Chemically induced (ENU)
Gene  Themis Inheritance Mode  Recessive
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false Project Collection  Beutler Mutagenetix
molecularNote  ENU mutagenesis induced an A to G transition at base pair 28,782,011 (v38) on chromosome 10, or base pair 113,685 in the GenBank genomic region NC_000076. The mutation results in an arginine (R) to glycine (G) substitution at position 345 (R345G) and is strongly predicted by Polyphen-2 to cause loss of function (score = 1.00).
  • mutations:
  • Single point mutation
  • synonyms:
  • currant,
  • currant
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele