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Allele : Wee2<em1(IMPC)J> WEE1 homolog 2 (S. pombe); endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:5576529 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Wee2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele, from project Wee2-5717J-4922, was generated by injecting Cas9 RNA and guide sequence GACTGCACAAGACATCGG into fertilized C57BL/6NJ oocytes, which resulted in an 8 bp deletion CAAGACAT in exon2 beginning at Chromosome 6 positive strand position 40444071 bp (GRCm38). It is predicted to cause a frameshift mutation with an amino acid change of glutamine to arginine after residue 31 and early truncation 13 residues later.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Wee2<em1J>,
  • Wee2<em1J>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

4 Publication categories