Primary Identifier | MGI:5576529 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Wee2 |
Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
Is Recombinase | false | Is Wild Type | false |
Project Collection | IMPC |
molecularNote | This allele, from project Wee2-5717J-4922, was generated by injecting Cas9 RNA and guide sequence GACTGCACAAGACATCGG into fertilized C57BL/6NJ oocytes, which resulted in an 8 bp deletion CAAGACAT in exon2 beginning at Chromosome 6 positive strand position 40444071 bp (GRCm38). It is predicted to cause a frameshift mutation with an amino acid change of glutamine to arginine after residue 31 and early truncation 13 residues later. |