| Primary Identifier | MGI:5582321 | Allele Type | Targeted |
| Attribute String | Not Specified | Gene | Myh11 |
| Transmission | Germline | Strain of Origin | 129S/SvEv |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of a modified exon 7 in which a C to T point mutation results in the amino acid substitution of cysteine for arginine at position 247 (R247C). This mutation mimics a rare variant identified in humans. Flp-mediated recombination removed an FRT flanked neomycin resistance cassette inserted downstream of exon 8, leaving single loxP and FRT sites. |
