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Allele : Ins1<tm2.1(cre/ERT2)Thor> insulin I; targeted mutation 2.1, Bernard Thorens
Primary Identifier  MGI:5614361 Allele Type  Targeted
Attribute String  Inducible, Null/knockout, Recombinase Gene  Ins1
Transmission  Germline Strain of Origin  C57BL/6J
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  A targeting construct was designed to insert a cre recombinase gene fused with a modified estrogen receptor gene (cre/ERT2) at the initiation codon of the gene with followed by a FRT-flanked neomycin resistance (neo) cassette, replacing the coding sequence. Flp-mediated recombination removed the FRT-flanked neo cassette.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • MIP1-CreERT2,
  • Ins1<CreERT2>,
  • Ins1<CreERT2>,
  • MIP1-CreERT2
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

18 Publication categories





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