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Allele : Mlkl<tm1.2Wsa> mixed lineage kinase domain-like; targeted mutation 1.2, Warren S Alexander

Primary Identifier  MGI:5614464 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mlkl
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  A FRT site flanked neomycin resistance cassette was inserted in intron 3 along with loxP sites upstream of exon 3 and immediately downstream of the resistance cassette. The neo cassette was removed via Flp-mediated recombination and the loxP flanked exon 3 was deleted via Cre-mediated recombination. Western blot analysis confirmed absence of protein in all tissues examined.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

93 Publication categories