| Primary Identifier | MGI:5629667 | Allele Type | Targeted |
| Attribute String | Not Specified | Gene | Fen1 |
| Transmission | Germline | Strain of Origin | 129S1/Sv |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The coding sequence was replaced with a cDNA with a G to A point mutation that results in an amino acid substitution of lysine for glutamic acid at position 359 (E359K). Cre-mediated recombination removed a floxed neomycin resistance cassette inserted upstream of the modified cDNA. Western blot analysis revealed a similar expression of FEN1 in wild-type and homozygous mutant mice. |
