Primary Identifier | MGI:5629850 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Pagr1a |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 1 and 2 were deleted. Whole-mount in situ hybridization confirmed absence of expression in a homozygous mutant embryo at the late allantoic bud stage/early head fold stage. Absence of detectable mRNA corresponding to exon 3, which is retained in the deleted allele, may be due either to lack of transcription initiation or to mRNA instability, suggesting that the allele is a complete null. |